Magnetic Separation

The magnetic stands are designed to guarantee optimal results in combination with magnetic particle kits. Naturally stands could also be used with each other kit on the basis of magnetic particles.

 

Magnetic stands consist out of variably sized transparent acrylic glass (Plexiglas) blocks allowing users permanent optical control of magnetic separation. All used magnets are durable, extra strong permanent magnets which guarantee a very fast magnetic separation in varying sample volumes.

 

We offer customers a broad range of magnetic stands for different sample- and elution volumes and applications. The assortment ranges from the “normal” magnetic separator M96 for applications in 96 well plate format, M12+12 stands for 1.5ml/ 2.0ml tubes, M96 deep well plate separators up to XXL stands for 5-50ml applications.

 

Furthermore it is possible to adapt magnetic separators in addition to manual use to different robotic systems (with SBS standard format). Thus the manual magnetic separator M96 is also available as adaptation for JobiWell robotic system former from Cybio AG/ Jena and for RoboAmp and RoboSeq robotic systems former from MWG Biotech/Aviso GmbH. In cooperation with you it is also possible to design magnetic stands for your requirements.

 

Magnetic stands are commonly used in biotechnology for various applications, such as cell separation, purification of biomolecules, and detection of biological targets. Here are some examples of how magnetic stands can be used in biotechnology:

  1. Cell separation: Magnetic stands can be used for the isolation and separation of specific cells from a heterogeneous cell population. This technique is commonly used in immunology and cancer research. Magnetic beads coated with specific antibodies are added to the cell mixture, which binds to the target cells. The mixture is then placed on a magnetic stand, which captures the magnetic beads and the target cells, while the non-target cells are removed by washing. The target cells can be eluted from the magnetic beads for further analysis.
  2. Purification of biomolecules: Magnetic stands can be used for the purification of biomolecules, such as DNA, RNA, and proteins. Magnetic beads coated with specific ligands, such as streptavidin or antibodies, are added to the mixture containing the biomolecule of interest. The mixture is then placed on a magnetic stand, which captures the magnetic beads and the biomolecule of interest. The non-specific contaminants can be removed by washing, and the purified biomolecule can be eluted from the magnetic beads.
  3. Detection of biological targets: Magnetic stands can be used for the detection of biological targets, such as viruses, bacteria, and cancer cells. Magnetic beads coated with specific ligands, such as antibodies or aptamers, are added to the sample containing the target. The mixture is then placed on a magnetic stand, which captures the magnetic beads and the target. The detection of the target can be done by various methods, such as fluorescence, chemiluminescence, or electrochemical detection.

In summary, magnetic stands are versatile tools that can be used in various applications in biotechnology. The principle behind the use of magnetic stands is the capture of magnetic beads, which are coated with specific ligands or antibodies, and the separation or detection of the target of interest.

 

Please request for individual solutions.